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We know that long-duration proton pump inhibitor (PPI) use is often associated with lower magnesium levels and deficiency. Meacham says

J Orthop Transl (2018) 12:6673

Hahm JY, Park J, Jang ES, Chi SW

QLQX being a multi-herb combination, has a lower risk of specific cytochrome-mediated interactions (since its not a single high-concentration alkaloid), but it can still interact pharmacodynamically with cardiac drugs